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In a January 2019 article, in which seven MVD-affected dogs (2 CKCSs) in CHF were tested, the researchers found that synthetic canine BNP1-32 produced no measurable beneficial cardio-renal effects, leading them to suggest that dogs with chronic CHF may have a reduction in natriuretic peptide responsiveness

Hepatic encephalopathy (HE) represents a broad neuropsychiatric syndrome that arising from a consequence of acute or chronic hepatic failure.1 Its symptoms may or may not be clinically apparent, but always impair function and quality of life